Abstract
The tuberculosis study subjects were diagnosed on the basis of sputum microscopic examination. Tuberculosis is a chronic, communicable and infectious disease mainly caused by Mycobacterium tuberculosis. This case-control study was carried out among 104 MDR-TB cases and 104 drug sensitive tuberculosis cases as controls. Among cases and controls 66(63.5%) male and 38(36.5%) female tuberculosis patients were on treatment for tuberculosis under district tuberculosis centre Satara. Most of the study participants from both cases and controls group were from rural area. The male predominance was seen in both drug resistant and drug sensitive tuberculosis. Majority of study subject from cases (70.2%) and controls (68.3%) belonged to age group 19 to 40 years of age. So it was concluded that the primary infection that the patients have got is due to multidrug resistance tuberculosis contact. Among medical condition asthma found to be significantly associated with multidrug resistance tuberculosis.

Key words: Multidrug, Tuberculosis, Treatment, MDR, Mycobacterium