E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research (Original Article) 


Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali.

Abstract
Back ground: Clinical trials are testing many types of treatment such as new drugs, new methods of surgery or radiotherapy, new combinations or new methods such as gene therapy, and clinical trials are one of the final stages of a long and accurate cancer research process.

Methods: As the search for new treatments begins in the laboratory, scientists invent and test new ideas first. If this approach is promising, the next step will be animal testing to see how it affects cancer in an organism, and whether it has harmful effects. Of course, treatments that work well in the laboratory or in animals may not work well in humans.

Results: The research aimed find better ways to treat cancer patients for this ,the studies are carried out on cancer patients to see if the treatment is promising, safe and effective. We attended three innovative derivatives in which two important pharmaceutical drugs were linked to the innovative sulfazane group for development and obtaining three pharmaceutical compounds developed for cancer treatment, via a series of chemical reactions to prepare the derivatives and linking them to two pharmaceutical drugs for their development and the use of non-previously used catalysis agents and innovative reaction conditions to ensure an ideal preparation method and as a reference for the upcoming research of such sulfazane compounds.

Conclusions: The derivatives (Gluta. Cefixime-Sulfazane) were proven by several diagnostic methods to prove their chemical composition act ((FT.IR - Spectra, H.NMR Spectra, HMBC- Spectrum, Mass Spectra), chemical properties, Flowing via TLC. Then studies of cancerous cells (Throat Cancer) and other normal cells were conducted to determine their efficiency in treatment and their toxic effect.,all these evidences gave good data proved invented drugs.

Key words: Throat Cancer, Sulfazane, glutathione, cefixime, innovation, new reaction of diazonium, sulfide-azo, (-S-N=N-), invented compounds, tumor, cancer, toxicity.


 
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How to Cite this Article
Pubmed Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. . 2020; 11(2): 44-55. doi:10.31838/jcdr.2020.11.02.09


Web Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. http://www.jcdronline.org//?mno=118251 [Access: June 25, 2020]. doi:10.31838/jcdr.2020.11.02.09


AMA (American Medical Association) Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. . 2020; 11(2): 44-55. doi:10.31838/jcdr.2020.11.02.09



Vancouver/ICMJE Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. . (2020), [cited June 25, 2020]; 11(2): 44-55. doi:10.31838/jcdr.2020.11.02.09



Harvard Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali (2020) Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. , 11 (2), 44-55. doi:10.31838/jcdr.2020.11.02.09



Turabian Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. 2020. Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. Journal of Cardiovascular Disease Research, 11 (2), 44-55. doi:10.31838/jcdr.2020.11.02.09



Chicago Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. "Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors." Journal of Cardiovascular Disease Research 11 (2020), 44-55. doi:10.31838/jcdr.2020.11.02.09



MLA (The Modern Language Association) Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali. "Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors." Journal of Cardiovascular Disease Research 11.2 (2020), 44-55. Print. doi:10.31838/jcdr.2020.11.02.09



APA (American Psychological Association) Style

Imad Kareem Alwan Alsabri, Hasaneen Kudhair Abdullabass, Nagham Mahmood Aljamali (2020) Invention of (Gluta. Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. Journal of Cardiovascular Disease Research, 11 (2), 44-55. doi:10.31838/jcdr.2020.11.02.09