E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research (Original Article) 


Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji.

Abstract
Background: both ischemic heart disease (IHD) and dental caries (DCr) are a chronic multifactorial disorder sharing several etiopathological risk factors. Uric acid (UA) has a proved pro inflammatory effect. This work is an attempt evaluate the causal effect of UA in carious experience in IHD patients.

Material and Methods: 118 IHD patients clinically assessed by cardiologist and 50 healthy subjects has been selected as a control group. One-way ANOVA was applied to correlate SUA level with groups of DMFT index. DCr was evaluated according to DMFT-index based on WHO-recommendations 1997. All participants were divided according to their carious status into three classes in which a DMFT index. All participants investigated for serum levels of uric acid, creatinine, urea nitrogen, according to available conventional techniques, and their serum UA/creatinine ratio had been calculated. Then again, studied subjects divided into normouricemic and hyperuricemic, using a cutoff level of 7.0mg/dl for males and 6.0mg/dl for females were assigned. Results are presented as mean±SD. The variation and correlation among variables were allocated significant for all the tests, once p-value ≤0.05. The data was processed and analyzed using SPSS version25 IBM-USA.

Results: The overall index of DCr in studied subjects was 11.7. Higher, not significant levels of SUA observed among patients (p-0.43). Significantly higher DMFT among IHD patients compared to control [14.6±10.8, vis 5.0±5.0, p-0.00 one-to-one]. Mean SUA/creatinine ratio was significantly higher in the patients' group (0.017). Gender revealed no impact regarding variation in the mean sera levels of UA and carious status among all studied subjects. Its observed that about half of the applicants had bad carious scores (DMFT>10). DMFT-scores increased bluntly as the ratio of mean SUA/creatinine increased among IHD patients but not in control group.
Conclusion: Patients with IHD had significantly higher caries experiences. Positive nonsignificant association of DCr with hyperuricemic subjects. Positive nonsignificant association of hyperuricemia and IHD. Significant higher SUA/creatinine ratio among the IHD as well as among those with carious experience.

Key words: uric acid, heart diseases, hyperuricemia


 
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How to Cite this Article
Pubmed Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. . 2020; 11(2): 137-143. doi:10.31838/jcdr.2020.11.02.21


Web Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. http://www.jcdronline.org//?mno=119187 [Access: June 27, 2020]. doi:10.31838/jcdr.2020.11.02.21


AMA (American Medical Association) Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. . 2020; 11(2): 137-143. doi:10.31838/jcdr.2020.11.02.21



Vancouver/ICMJE Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. . (2020), [cited June 27, 2020]; 11(2): 137-143. doi:10.31838/jcdr.2020.11.02.21



Harvard Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji (2020) Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. , 11 (2), 137-143. doi:10.31838/jcdr.2020.11.02.21



Turabian Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. 2020. Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. Journal of Cardiovascular Disease Research, 11 (2), 137-143. doi:10.31838/jcdr.2020.11.02.21



Chicago Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. "Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study." Journal of Cardiovascular Disease Research 11 (2020), 137-143. doi:10.31838/jcdr.2020.11.02.21



MLA (The Modern Language Association) Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji. "Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study." Journal of Cardiovascular Disease Research 11.2 (2020), 137-143. Print. doi:10.31838/jcdr.2020.11.02.21



APA (American Psychological Association) Style

Amir Al-Mumin, Mazin Jaafar Mousa, Ahlam Kadhim Abbood, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji (2020) Causal-Effect of Uric Acid and Caries Experience in Ischemic Heart Diseases: A Case-Control Study. Journal of Cardiovascular Disease Research, 11 (2), 137-143. doi:10.31838/jcdr.2020.11.02.21