E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research 


Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader.

Abstract
Based on Amiloride hydrochloride-methyl orange, two electrodes of Amiloride hydrochloride were constructed in PVC matrix as ion pair complex. They were plasticized using Nitrobenzene (NB), and Di-butyl phosphate (DBP). Amiloride hydrochloride (AMH) electrodes (e1and e2) presented slopes (54.210 and 52.810 mV/decade) and linear ranges (10-5-10-2, and 2*10-5-10-2 M), respectively. (e1), which is the best electrode, was based on DBP plasticizer. It gave a detection limit of 4x10-6M, slope of 54.210 mV/decade, correlation coefficient 0.9998, lifetime 36 days. The proposed electrode displayed reproducibility and good stability and was used for determining Amiloride hydrochloride in pharmaceutical samples. The interference measurements using (Na+, Cu+2, K+, Fe+3, and Mn+2) were studied for selectivity coefficient determination using the separated method, as well as the mixed method

Key words: Ploymeric electrodeas, reproducibility.


 
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How to Cite this Article
Pubmed Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26


Web Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. http://www.jcdronline.org//?mno=16909 [Access: October 21, 2020]. doi:10.31838/jcdr.2020.11.04.26


AMA (American Medical Association) Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26



Vancouver/ICMJE Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26



Harvard Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader (2020) Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26



Turabian Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. 2020. Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26



Chicago Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. "Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination." doi:10.31838/jcdr.2020.11.04.26



MLA (The Modern Language Association) Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader. "Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination." doi:10.31838/jcdr.2020.11.04.26



APA (American Psychological Association) Style

Sarra A. Abrahem, Suhad A. Ibrahim, Abdul kader Saad Abdul kader (2020) Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination. doi:10.31838/jcdr.2020.11.04.26





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