E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana.

Abstract
Introduction: Endothelial Dysfunction(ED) is produced by oxidation stress, breakdown and inactivation of nitric oxide, prostanoids, endothelin 1 leading to decreased bioavailability of NO sustained SBP and high mean BP blunts Flow Mediated Dilatation (FMD) response in brachial artery. This particular study has been carried out to analyze brachial artery flow-mediated vasodilatation by ultrasonographic imaging with high resolution along with pulse Doppler study.

Material and Methods: This study has been carried out in a tertiary care hospital, Visakhapatnam during the session August 2018 to December 2019.Fifty hypertensive patients diagnosed as per JNC-VIII recommendation have been studied. Thirty males and twenty females have been taken as control for comparison. Evaluation of their endothelial function was done in terms Resting Brachial Artery Diameter (RBAD) and FMD% in hypertension group.

Results: In the present study serum cholesterol value in hypertension has found to be 174 18.02 mg/dl, whereas, its value in control is 170.6 20.5 mg/dl. HDL value found to be 47.70 6.4 mg/dl in hypertension, 47.51 6.50 with LVH and 48.12 4.99 without LVH and in control; it is 42.6 9.34 mg/dl. HDL value which is known to be protective against atherosclerosis did not show positive correlation with FMD%.

Conclusion: FMD% may not be useful for therapeutic purpose because large number of physiological factor alters this. It is a functional bioassay for, in vivo, endothelial function in human.

Key words: Flow-mediated Dilatation, Brachial Artery Diameter, Endothelial Dysfunction, Hypertensive, FMD, Parameters.


 
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Pubmed Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44


Web Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. http://www.jcdronline.org//?mno=17873 [Access: October 22, 2020]. doi:10.31838/jcdr.2020.11.04.44


AMA (American Medical Association) Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44



Vancouver/ICMJE Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44



Harvard Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana (2020) Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44



Turabian Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. 2020. Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44



Chicago Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. "Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters." doi:10.31838/jcdr.2020.11.04.44



MLA (The Modern Language Association) Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana. "Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters." doi:10.31838/jcdr.2020.11.04.44



APA (American Psychological Association) Style

V.V.N. Goutham, Samir Kumar Panda, Mrudula Vandana (2020) Relationship Analysis between Flow Mediated Dilatation of Brachial Artery and Hypertension along with Other Related Parameters. doi:10.31838/jcdr.2020.11.04.44





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