E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research 


Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human

Abdullatif A. Aljuboury, Sinan Subhi Farhan.

Abstract
The complements play an essential active role in the gingival inflammation, their roles have been studied in the connective tissues, in the crevicular fluid and in the peripheral blood as well. Unfortunately, the circulating peripheral blood cannot reflect a real picture of the immunologic reactions in the gingiva. In addition, the quantification of complement concentration in the gingival fluid or in the tissue could not been measured before. This study tries to quantify the amount of C1, C3 and C5 complement compounds in the gingival blood as a closest source to the site of inflammatory process of the gingiva. And to find a correlation between their concentrations compared to the inflammation severity. Twenty volunteers, dentistry students, sampled their gingival blood in three events, healthy gingiva, early disease, then returned to healthy state. The sera studied with the immuno-Nephelometer after a specific preparation. A specific antibody anti complements C1, C3 and C5 have been used to form a specific antigen-antibody complex in vitro. The results showed a significant increase in amount of C1, C3 and C5 (P<O.O5) plus a positive correlation with the progression or regression of the inflammatory process. These complements showed a positive significant correlation (P<0.05) with the GI of disease progression, but insignificant with regression. In conclusion, the gingival blood could give a close immunologic feature of immunologic changes of gingiva during health or disease.

Key words: Complements, Immuno-Nephelometer, Gingival Blood, Experimental Gingivitis.


 
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Pubmed Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48


Web Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. http://www.jcdronline.org//?mno=17901 [Access: October 23, 2020]. doi:10.31838/jcdr.2020.11.04.48


AMA (American Medical Association) Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48



Vancouver/ICMJE Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48



Harvard Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan (2020) Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48



Turabian Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. 2020. Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48



Chicago Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. "Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human." doi:10.31838/jcdr.2020.11.04.48



MLA (The Modern Language Association) Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan. "Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human." doi:10.31838/jcdr.2020.11.04.48



APA (American Psychological Association) Style

Abdullatif A. Aljuboury, Sinan Subhi Farhan (2020) Nephelometric Quantification of Complement C1, C3 and C5 Components of Gingival Blood, From Health to Early Disease. Experimental Study on Human. doi:10.31838/jcdr.2020.11.04.48





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