E-ISSN 0976-2833 | ISSN 0975-3583
 
2020, Vol: 11, Issue: 4
11 / 4Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles
Required files to be uploaded

Author Contribution Form _(v2r)_
Copyright Form_(v2r)_

Original Research (Original Article) 


Reduced nitrate level in individuals with hypertension and diabetes

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi.

Abstract
Background: Nitric oxide (NO) turnover is vital for proper endothelial function to maintain a healthy vascular
system. Various risk factors responsible for hypertension and diabetes may disrupt this homeostasis, leading to
decreased bioavailability and/or bioactivity of NO, which potentiates endothelial dysfunction. Plasma NO is a
useful indicator of NO homeostasis and vascular endothelial function. Since endothelial function plays a key
role in the development and progression of diseases like diabetes and hypertension, we sought to investigate
the NO profile in patients having diabetes and hypertension and determine the relationship of NO turnover
with the disease. Materials and Methods: For this purpose, three groups were studied for the NO production.
The first group consisted of 74 hypertensive patients, the second group consisted of 72 diabetic patients and
the third group consisted of 60 healthy controls. Nitrate synthase activity was evaluated by measuring nitrate
level using an automated sample injector connected to an automated NO detector – Ion liquid chromatograph.
Results: The plasma concentration of NO was found to be significantly lower in both essential hypertensive
patients and diabetic patients without complications as compared to the healthy controls (P < 0.05). Conclusion:
This data confirms that different factors like hyperglycemia and blood pressure are seen to have immense
influence on NO production.

Key words: Diabetes, hypertension, nitric oxide


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Shiekh Gazalla Ayub
Articles by Taha Ayub
Articles by Saquib Naveed Khan
Articles by Rubiya Dar
Articles by Khurshid Iqbal Andrabi
on Google
on Google Scholar
Article Statistics
 Viewed: 1
Downloaded: 0


How to Cite this Article
Pubmed Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. Reduced nitrate level in individuals with hypertension and diabetes. . 2011; 2(3): 172-176. doi:10.4103/0975-3583.85264

Web Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. Reduced nitrate level in individuals with hypertension and diabetes. http://www.jcdronline.org//?mno=93180 [Access: March 27, 2020]. doi:10.4103/0975-3583.85264

AMA (American Medical Association) Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. Reduced nitrate level in individuals with hypertension and diabetes. . 2011; 2(3): 172-176. doi:10.4103/0975-3583.85264


Vancouver/ICMJE Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. Reduced nitrate level in individuals with hypertension and diabetes. . (2011), [cited March 27, 2020]; 2(3): 172-176. doi:10.4103/0975-3583.85264


Harvard Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi (2011) Reduced nitrate level in individuals with hypertension and diabetes. , 2 (3), 172-176. doi:10.4103/0975-3583.85264


Turabian Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. 2011. Reduced nitrate level in individuals with hypertension and diabetes. Journal of Cardiovascular Disease Research, 2 (3), 172-176. doi:10.4103/0975-3583.85264


Chicago Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. "Reduced nitrate level in individuals with hypertension and diabetes." Journal of Cardiovascular Disease Research 2 (2011), 172-176. doi:10.4103/0975-3583.85264


MLA (The Modern Language Association) Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi. "Reduced nitrate level in individuals with hypertension and diabetes." Journal of Cardiovascular Disease Research 2.3 (2011), 172-176. Print. doi:10.4103/0975-3583.85264


APA (American Psychological Association) Style

Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi (2011) Reduced nitrate level in individuals with hypertension and diabetes. Journal of Cardiovascular Disease Research, 2 (3), 172-176. doi:10.4103/0975-3583.85264




Most Viewed Articles
  • Reduced nitrate level in individuals with hypertension and diabetes
    Shiekh Gazalla Ayub, Taha Ayub, Saquib Naveed Khan, Rubiya Dar, Khurshid Iqbal Andrabi
    . 2011; 2(3): 172-176
    » Abstract » doi: 10.4103/0975-3583.85264

  • Factor analysis of risk variables associated with metabolic syndrome in adult Asian Indians
    Mithun Das, Susil Pal, Arnab Ghosh
    . 2010; 1(2): 86-91
    » Abstract » doi: 10.4103/0975-3583.64442

  • Typical coronary artery aneurysm exactly within drug-eluting stent implantation region in a patient with rheumatoid arthritis
    Ying Zheng, Jing-yuan Mao
    . 2012; 3(4): 329-331
    » Abstract » doi: 10.4103/0975-3583.102725

  • Putative antioxidant property of sesame oil in an oxidative stress model of myocardial injury
    Mohamed T.S. Saleem , Madhusudhana C. Chetty , S. Kavimani
    . 2013; 4(3): 177-181
    » Abstract » doi: 10.1016/j.jcdr.2013.07.001

  • Medical and Social Characteristics and Quality of Life of Children with Urinary System Diseases (on the Example of Urinary System Infection)
    A.A. Maksimova, N.V. Savvina, N.M. Gogolev, A.I. Protopopova
    . 2020; 11(2): 194-201
    » Abstract » doi: 10.31838/jcdr.2020.11.02.33

    •
    Most Downloaded
  • Diabetic Retinopathy, The Automated of Detection of Retinal Fundus Images with Probabilistic Neural Networks (PNN)
    Elvina Amanda, Marischa Elveny, Rahmad Syah
    . 2020; 11(4): 302-306
    » Abstract » doi: 10.31838/jcdr.2020.11.04.54

  • Assessment of the Knowledge and Attitude of Male Students towards Smoking Based on Health Belief Model
    Rafat Rezapour-Nasrabad, Fatemeh Izadi, Atousa Karimi, Fateme Shariati Far, Khatereh Rostami, Amin Kiani, Afsaneh Ghasemi
    . 2020; 11(4): 116-121
    » Abstract » doi: 10.31838/jcdr.2020.11.04.20

  • Investigation of the Relationship between Social Support and Adherence to Treatment among Elderly Individuals with Type II Diabetes Mellitus
    Afsaneh Ghasemi, Rafat Rezapour-Nasrabad, Leila Nikrouz, Fatemeh Izadi, Atousa Karimi, Fateme Shariati Far, Zahra Khiali
    . 2020; 11(4): 122-129
    » Abstract » doi: 10.31838/jcdr.2020.11.04.21

  • Cardio-Vascular Disease Classification Using Stacked Segmentation Model and Convolutional Neural Networks
    G. Charlyn Pushpa Latha, S. Sridhar, S. Prithi, T. Anitha
    . 2020; 11(4): 26-31
    » Abstract » doi: 10.31838/jcdr.2020.11.04.05

  • Strategic DOTS to Increase Medical Knowledge for the Treatment of TB Patients
    Elvina Amanda, Marischa Elveny, Rahmad Syah
    . 2020; 11(4): 296-301
    » Abstract » doi: 10.31838/jcdr.2020.11.04.53

    •
    Most Cited Articles
    This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
    The articles in Journal of Cardiovascular Disease Research are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
    Copyright © 2021 Journal of Cardiovascular Disease Research All Rights Reserved. Subject to change without notice from or liability to Journal of Cardiovascular Disease Research.
    For best results, please use Internet Explorer or Google Chrome

    Contact Information



    Branch Office/Support Office for journal:

    Journal of Cardiovascular Disease Research 

    Publication Office

    Advanced Scientific Research,
    21, Thyamotharan Street, Arisipalayam
    Salem - 636009

    Email : editor@jcdronline.org 

    support : support@jcdronline.org

     
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use