COMPARISON OF INTRAVENOUS PARACETAMOL VERSUS ORAL IBUPROFEN FOR THE CLOSURE OF HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS IN PRETERM AND TERM NEONATES: AN OPEN-LABEL RANDOMIZED STUDY

Abstract

Background: Patent ductus arteriosus is a common congenital heart defect among preterm neonates. Preterm newborns with prolonged ductal patency have been linked to considerable short- and long-term morbidities, as well as higher mortality; however, systematic treatment of everyone during the neonatal period has resulted in a detectable improvement in long-term results