INTRAOPERATIVE AND POSTOPERATIVE EFFECTS OF DEXMEDETOMIDINE ON HAEMODYNAMIC STRESS RESPONSES TO SURGERIES

Abstract

Introduction : . Stress response to surgery is characterized by increase in secretion of endocrinal 
system and activation of immunological and sympathetic nervous system. Alpha 2-adrenoceptor 
agonists have several beneficial actions during the perioperative period. They decrease sympathetic 
tone, with attenuation of the neuroendocrine and hemodynamic responses to anaesthesia and 
surgery; reduce anaesthetic and opioid requirements; and cause sedation and analgesia