COMPARISION OF TWO DIFFERENT DOSES OF HYPERBARIC LEVOBUPIVACAINE AND HYPERBARIC RACEMIC BUPIVACAINE WITH FENTANYL AS AN ADJUVANT IN PATIENTS UNDERGOING CAESAREAN SECTION, A PROSPECTIVE RANDOMIZED CONTROL STUDY

Abstract

BACKGROUND The pure S (–) enantiomer of racemic bupivacaine is known as levobupivacaine. When compared to bupivacaine, it has a lower potency for motor blockade and a similar clinical profile, but it has a safer profile with a lower risk of toxicity. When intrathecal opioids are combined with local anaesthetics, the well-established synergistic effect is achieved without exacerbating motor and sympathetic blockades. This allows for the successful administration of a low-dose local anaesthetic, leading to more stable haemodynamics throughout the anaesthesia. The current study aimed to compare low-dose bupivacaine with low-dose levobupivacaine in terms of their clinical efficacy and blockade quality when paired with fentanyl in caesarean section.