Preclinical Study of Derivative of 3-Oxypiridone in Experimental Pre-Eclampsia

Authors

  • Alesya V. Yurakova, Sofya Y.Skachilova, Lyudmila M.Danilenko, Indira S. Kochkarova, Natalia V.Ekimova, Anastasia V. Gureeva, Il'ya S. Rozhkov, Adelaida V. Polyanskaya Author

DOI:

https://doi.org/10.48047/

Keywords:

preeclampsia, 3-oxypiridine, mexidol, endothelial dysfunction, rats, proteinuria, microcirculation

Abstract

Introduction: Currently, preeclampsia remains a serious multisystem complication of pregnancy, leading to disability of children and maternal mortality. One of the leading theories of pathogenesis is the theory of oxidative stress. Accordingly, the search for new drugs with antioxidant and antihypoxic effects is promising for the prevention and treatment of preeclampsia. 

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Published

2020-10-11

Issue

Vol. 11 No. 4 (2020): volume 11 issue 4 (2020)

Section

Articles