A Randomized Double Blind Comparative Study Of Fentanyl And Dexmedetomidine As Intrathecal Adjuvants To 0.75% Hyperbaric Ropivacaine In Lower Limb Orthopaedic Surgeries.

Abstract

Background: Ropivacaine, a long-acting amide local anesthetic agent, is a pure S enantiomer of bupivacaine. 
Intrathecal adjuvants have been used with local anesthetics for better hemodynamics and to provide 
postoperative analgesia. In this study we used Dexmedetomidine in comparison with Fentanyl, as an intrathecal 
adjuvant. The aim of this study is to evaluate the onset and duration of sensory and motor block, hemodynamic 
effect, and adverse effects of Dexmedetomidine or Fentanyl given intrathecally with hyperbaric 0.75% 
Ropivacaine.