Innovative Strategies for Enhancing Neuroplasticity in Stroke Recovery Clinical Applications and Future Directions

Abstract

Stroke remains a leading cause of long-term disability, significantly impacting quality 
of life. Neuroplasticity—the brain's ability to reorganize itself by forming new neural 
connections—is crucial for recovery post-stroke. The research compares promising 
new treatments for neuroplasticity, such as drugs, non-invasive brain stimulation and 
cutting-edge rehabilitation. These techniques are evaluated in a 12-week randomised 
controlled trial with 120 stroke patients and their findings are reported in four tables: 
motor and cognitive function improvement, functional connectivity, and patient 
satisfaction. Results indicate that combination therapies – TMS in conjunction with 
task-directed training – are most effective and provide a promising avenue for 
individualised neurorehabilitation