E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD.

Abstract
Introduction: The life expectancy increase is steadily leading to the fact that more and more severe patients
begin to undergo surgical treatment of coronary artery disease. Off-pump coronary artery bypass grafting may be
the operation of choice in treating this category of patients.
Objective: To study the immediate results of surgical treatment of coronary artery disease using Off-pump
myocardial revascularisation in patients with a high risk of mortality and complications.
Materials and Methods: The study summarised the results of surgical treatment of 1339 high-risk patients with
coronary artery disease who were operated on in the period from 2003 to 2015, of which 672 - using the Offpump
revascularisation and 667 - using the conventional On-pump CABG with cardio-pulmonary bypass. The
groups were comparable in age: the mean age in the Off-pump group was 69.6 7.4 years, and in the On-pump
group - 69.8 7.7 years (p = 0.874).
Results: In both groups, most often, multivessel coronary artery bypass grafting was performed. In the Offpump
group, revascularisation of three or more coronary arteries was performed in 519 (77.3%) patients, and the
On-pump group - in 521 (78.22%); there was no statistical difference (p = 0.699). The mean total duration of
surgery was 5.3 1.6 hours in the Off-pump group and 5.22 1.3 hours in the On-pump group and had no
significant difference (p = 0.3165). The intraoperative need for intra-aortic balloon pump counterpulsation in the
On-pump group was significantly higher than in the Off-pump group (p = 0.0002). A significantly lower (p
<0.05) number of cerebral and renal complications in the postoperative period was revealed in patients
undergoing Off-pump myocardial revascularisation. In the general group of high-risk patients, both groups did
not significantly differ in the frequency of deaths. Thus, in the Off-pump group, the frequency of deaths was
3.4% (23 patients) and in the On-pump group - 5.4% (36 patients) (p = 0.0785). In the On-pump CABG group,
mortality in female patients was higher than in the Off-pump group (p = 0.031).
Conclusions: Based on the data obtained, it was concluded that Off-pump myocardial revascularisation is highly
effective in the surgical treatment of high-risk patients.

Key words: ischemic heart disease, CABG, surgical treatment, Off-pump, high risk, immediate results


 
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How to Cite this Article
Pubmed Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. J Cardiovasc. Dis. Res.. 2021; 12(5): 105-109. doi:10.31838/jcdr.2021.12.05.17


Web Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. http://www.jcdronline.org/?mno=105716 [Access: August 03, 2021]. doi:10.31838/jcdr.2021.12.05.17


AMA (American Medical Association) Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. J Cardiovasc. Dis. Res.. 2021; 12(5): 105-109. doi:10.31838/jcdr.2021.12.05.17



Vancouver/ICMJE Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. J Cardiovasc. Dis. Res.. (2021), [cited August 03, 2021]; 12(5): 105-109. doi:10.31838/jcdr.2021.12.05.17



Harvard Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD (2021) OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. J Cardiovasc. Dis. Res., 12 (5), 105-109. doi:10.31838/jcdr.2021.12.05.17



Turabian Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. 2021. OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. Journal of Cardiovascular Disease Research, 12 (5), 105-109. doi:10.31838/jcdr.2021.12.05.17



Chicago Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. "OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS." Journal of Cardiovascular Disease Research 12 (2021), 105-109. doi:10.31838/jcdr.2021.12.05.17



MLA (The Modern Language Association) Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD. "OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS." Journal of Cardiovascular Disease Research 12.5 (2021), 105-109. Print. doi:10.31838/jcdr.2021.12.05.17



APA (American Psychological Association) Style

Adkham Jalilov, MD, PhD, Vadim Merzlyakov, MD, PhD, Ivan Klyuchnikov, MD, PhD, Alisher Melikulov MD, PhD, M. Salomov, MD, Timur Ruzmatov, MD, PhD,Rustam Yarbekov MD, PhD, Maksud Murodov MD, PhD (2021) OFF-PUMP CORONARY BYPASS IN HIGH-RISK PATIENTS. SHORT-TERM RESULTS. Journal of Cardiovascular Disease Research, 12 (5), 105-109. doi:10.31838/jcdr.2021.12.05.17





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