E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


ANTIVIRAL AGENTS FOR COVID-19: A Review

Nisha A Bhatt, Amandeep Singh, Shivam Saini.

Abstract
Covid -19 a virus caused by novel severe acute respiratory syndrome. It belongs to genus
Bettacoronavirus and family-Coronaviridae. In most of countries pandemic occured due to this virus, in Dec 2019 an
upsurge of covid-19 occurred in Wuhan city of China. WHO declared as public health emergency of international in
the month of Jan 2020? Covid-19 a RNA dependent virus which is composed of cap of crown like structure and
spike like protein located at outer part of virus these spikes are composed of glycoprotein .Various enzymes are in
maturation of life cycle of virus such chymotrypsin like protease, therefore main target for antiviral activity.The
emerging trend of Remdesivir a broad spectrum antiviral drug which shows potent effect in inhibiting viral
replication. Initialisation stage of attachment of virus through spike protein into host cell is also inhibited. In recent
study combination of Mycophenolic acid acyl glucronic with Remdesivir shows the potent inhibitory effect on
Covid-19. The side effects are not clear but in some clinical study acute inflammatory disease of kidney are seen. As
this drug after showing their inhibitory actions on viral replication also suppress the production of cytokines and due
to over suppression leads to cytokine mediated inflammatory disease.

Key words: Covid-19, Antiviral Drugs, Inflammation, Remdesivir


 
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Pubmed Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. ANTIVIRAL AGENTS FOR COVID-19: A Review. J Cardiovasc. Dis. Res.. 2021; 12(5): 218-223. doi:10.31838/jcdr.2021.12.05.33


Web Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. ANTIVIRAL AGENTS FOR COVID-19: A Review. http://www.jcdronline.org/?mno=107982 [Access: August 09, 2021]. doi:10.31838/jcdr.2021.12.05.33


AMA (American Medical Association) Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. ANTIVIRAL AGENTS FOR COVID-19: A Review. J Cardiovasc. Dis. Res.. 2021; 12(5): 218-223. doi:10.31838/jcdr.2021.12.05.33



Vancouver/ICMJE Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. ANTIVIRAL AGENTS FOR COVID-19: A Review. J Cardiovasc. Dis. Res.. (2021), [cited August 09, 2021]; 12(5): 218-223. doi:10.31838/jcdr.2021.12.05.33



Harvard Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini (2021) ANTIVIRAL AGENTS FOR COVID-19: A Review. J Cardiovasc. Dis. Res., 12 (5), 218-223. doi:10.31838/jcdr.2021.12.05.33



Turabian Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. 2021. ANTIVIRAL AGENTS FOR COVID-19: A Review. Journal of Cardiovascular Disease Research, 12 (5), 218-223. doi:10.31838/jcdr.2021.12.05.33



Chicago Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. "ANTIVIRAL AGENTS FOR COVID-19: A Review." Journal of Cardiovascular Disease Research 12 (2021), 218-223. doi:10.31838/jcdr.2021.12.05.33



MLA (The Modern Language Association) Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini. "ANTIVIRAL AGENTS FOR COVID-19: A Review." Journal of Cardiovascular Disease Research 12.5 (2021), 218-223. Print. doi:10.31838/jcdr.2021.12.05.33



APA (American Psychological Association) Style

Nisha A Bhatt, Amandeep Singh, Shivam Saini (2021) ANTIVIRAL AGENTS FOR COVID-19: A Review. Journal of Cardiovascular Disease Research, 12 (5), 218-223. doi:10.31838/jcdr.2021.12.05.33





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