E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi.

Abstract
Abstract
Background: Mortality and disease severity are decreased with appropriate antibiotic therapy
started timely especially in ICUs owing to widespread use concerning the admission of
postoperative subjects to ICU, considerable number of sepsis cases treated in ICU which can
cause antibiotic resistance in subjects who are severely ill.
Aims: The present study was conducted to assess the clinical impact and audit of implementing
an Antibiotic stewardship program in subjects admitted to adult surgical ICU settings of India.
Materials and Methods: The antibiotic audit was made by the expert pharmacologist for
subjects in surgical ICU, with the evaluation of how appropriate the prescribed antibiotic
therapies were. The suggestion was taken from a microbiologist for antibiotic susceptibility
and appropriateness of antibiotics, and a physician on the prescription of antibiotics. The
outcomes assessed in the present study were the use of a particular antibiotic, mean duration,
appropriateness of use, mortality within a month, source control documentation (by the
surgeon), and readmission without a prior plan. The collected data were subjected to statistical
evaluation.
Results: Mortality was 17.30% 9n=18) in pre-ASP and 14.15 (n=15) in post-ASP group. This
was statistically non-significant (p=0.69). Hospital stay duration and readmissions were also
statistically non-significant (p=0.2051 and 0.06 respectively) between the two groups. The
duration of antibiotics was higher for the pre-ASP group with p<0.001. Optimum antibiotic use
was seen in 23.07% (n=24) and 86.79% (n=92) subjects from pre-ASP and post-ASP group
Journal of Cardiovascular Disease Research

ISSN: 0975-3583, 0976-2833 VOL 12, ISSUE 06, 2021
491
respectively. Apt antibiotic selection was seen in 41.34% (n=43) and 74.52% (n=79) subjects
from pre-ASP and post-ASP group respectively (p<0.001). Source-control documentation was
not needed in any subject of the pre-asp group, whereas, in 62.26% (n=66) subjects of postASP it was needed (p<0.001).
Conclusion: The present study concludes that antibiotic duration, optimization, and
prescription can improve clinical parameters with ASP implementation. Also, complete
compliance of source-control documentation can improve antibiotic-related variables and
parameters in subjects undergoing surgery

Key words: Antibiotic audit, Antibiotic resistance, Antibiotic stewardship program, Infectious disease, surgical ICU.


 
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How to Cite this Article
Pubmed Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. J Cardiovasc. Dis. Res.. 2021; 12(6): 490-497. doi:10.31838/jcdr.2021.12.06.66


Web Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. http://www.jcdronline.org/?mno=23521 [Access: January 16, 2022]. doi:10.31838/jcdr.2021.12.06.66


AMA (American Medical Association) Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. J Cardiovasc. Dis. Res.. 2021; 12(6): 490-497. doi:10.31838/jcdr.2021.12.06.66



Vancouver/ICMJE Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. J Cardiovasc. Dis. Res.. (2021), [cited January 16, 2022]; 12(6): 490-497. doi:10.31838/jcdr.2021.12.06.66



Harvard Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi (2021) Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. J Cardiovasc. Dis. Res., 12 (6), 490-497. doi:10.31838/jcdr.2021.12.06.66



Turabian Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. 2021. Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. Journal of Cardiovascular Disease Research, 12 (6), 490-497. doi:10.31838/jcdr.2021.12.06.66



Chicago Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. "Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting." Journal of Cardiovascular Disease Research 12 (2021), 490-497. doi:10.31838/jcdr.2021.12.06.66



MLA (The Modern Language Association) Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi. "Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting." Journal of Cardiovascular Disease Research 12.6 (2021), 490-497. Print. doi:10.31838/jcdr.2021.12.06.66



APA (American Psychological Association) Style

Dr. Abhishek Kumar Shah, Dr Supratim Dasgupta, Dr. Rajendra Agarwal, Dr. Sreya Todi (2021) Antibiotic Prescription Audit in a Surgical Intensive Care Unit (ICU): A Clinical Study in the Indian Setting. Journal of Cardiovascular Disease Research, 12 (6), 490-497. doi:10.31838/jcdr.2021.12.06.66





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