E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research 


A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD)

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan.

Cited by (2)

Abstract
Background: Impairment in cognitive inhibition and flexibility is responsible for negative
cognitive bias in depression. There is inconsistency in research findings regarding cognitive
deficits underlying suicidal behaviour and its relationship with severity of depression and
scarce Indian studies.
Aim: This study aimed to study pattern of cognitive inhibition and mental flexibility in major
Depressive Disorder (MDD) subjects along with association between suicidal ideation and
cognitive deficits.
Method: This was a cross-sectional observational study conducted in the outpatient department
of a tertiary care centre. Eighty men with major depressive disorder diagnosed as per DSM5
were recruited and assessed using the Montgomery and Asberg Depression Rating Scale
(MADRS) for severity of depression, WCST (Wisconsin card sorting test) and Trail making
test A and B (TMT A, TMT B) were applied to assess the cognitive function of subjects. Beckís
Journal of Cardiovascular Disease Research

ISSN: 0975-3583, 0976-2833 VOL 12, ISSUE 06, 2021
507
scale for suicidal ideation (BSSI) was used for assessment of suicidal ideation. Other variables
were assessed using a semi-structured pro forma. Comparative analysis was done using student
t-test/Mann-Whitney U Test and Chi square test and one-way ANOVA. Correlation was done
using Pearson's correlation test.
Result: The WCST performance in ideator group was poorer than non ideators in Total Trials,
Total Errors and Categories Completed. The Total trials taken during card sorting in WCST
significantly correlated with severity of depression. There was significant positive correlation
between total trials and BSSI and negative correlation with categories completed.
Conclusion: The cognitive rigidity is a core characteristic of suicidality in MDD. The EF is
considered to be mostly widely used and validated tool. The current study studies the different
domains of executive function and comparatively analyses ideators, attempters and nonideators.

Key words: Cognitive Inflexibility, Executive Function(EF), Major depressive disorder, Suicide


 
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How to Cite this Article
Pubmed Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). J Cardiovasc. Dis. Res.. 2021; 12(6): 506-516. doi:10.31838/jcdr.2021.12.06.68


Web Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). http://www.jcdronline.org/?mno=29299 [Access: January 16, 2022]. doi:10.31838/jcdr.2021.12.06.68


AMA (American Medical Association) Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). J Cardiovasc. Dis. Res.. 2021; 12(6): 506-516. doi:10.31838/jcdr.2021.12.06.68



Vancouver/ICMJE Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). J Cardiovasc. Dis. Res.. (2021), [cited January 16, 2022]; 12(6): 506-516. doi:10.31838/jcdr.2021.12.06.68



Harvard Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan (2021) A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). J Cardiovasc. Dis. Res., 12 (6), 506-516. doi:10.31838/jcdr.2021.12.06.68



Turabian Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. 2021. A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). Journal of Cardiovascular Disease Research, 12 (6), 506-516. doi:10.31838/jcdr.2021.12.06.68



Chicago Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. "A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD)." Journal of Cardiovascular Disease Research 12 (2021), 506-516. doi:10.31838/jcdr.2021.12.06.68



MLA (The Modern Language Association) Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan. "A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD)." Journal of Cardiovascular Disease Research 12.6 (2021), 506-516. Print. doi:10.31838/jcdr.2021.12.06.68



APA (American Psychological Association) Style

Dr. Pankaj Kumar, Dr. Sikha Jha, Meha Jain, Dr. Santosh Kumar, Dr.Rajeev Ranjan (2021) A Study of Pattern of Cognitive Inflexibility and itís Relationship with Suicidal Behaviour in Patients with Major Depressive Disorder (MDD). Journal of Cardiovascular Disease Research, 12 (6), 506-516. doi:10.31838/jcdr.2021.12.06.68





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