E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research 


The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress

Endah Wulandari, Rr Ayu Fitri Hapsari, Ikrima Wulanuri, Afdalia Rani Nasution.

Abstract
Background: Heart organs can be damaged due to an increase in free radicals that are not balanced by antioxidants. Edible Birdís Nest (Collocalia fuciphaga) contains many amino acids and vitamins that are thought to stimulate antioxidant activity. The cardioprotective nature of swallow's nest is expected to be the basis of management for cases of heart disease.
Methods: The design of this study is experimental . This study showed levels of MDA (free radical decomposition), catalase activity (endogenous antioxidants) and histology of heart tissue after bieng given edible birdís nest extract (doses 10, 20 and 40 mg/kgBW) for 32 days.
Result: Edible Birdís extract was compared to the control: MDA levels decreased significantly (0.007; 0.038; 0.030 nmol/mg tissue), increased catalase activity (1.32; 1.21; 0.83 IU/mg tissue); Cardiomyocytes at 40x magnification showed a normal nucleus in the center.
Conclusion: Edible Birdís extract can suppress oxidative stress, through decreasing MDA, increasing catalase activity, and normal cardiomyocyte histology.

Key words: Edible Birdís (Collocalia fuciphaga), Antioxidants, Free radicals, Oxidative stress, Heart.


 
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How to Cite this Article
Pubmed Style

Wulandari E, Hapsari RAF, Wulanuri I, Nasution AR. The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. . 2021; 12(1): 75-81. doi:10.31838/jcdr.2021.12.01.20


Web Style

Wulandari E, Hapsari RAF, Wulanuri I, Nasution AR. The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. http://www.jcdronline.org//?mno=43513 [Access: May 01, 2021]. doi:10.31838/jcdr.2021.12.01.20


AMA (American Medical Association) Style

Wulandari E, Hapsari RAF, Wulanuri I, Nasution AR. The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. . 2021; 12(1): 75-81. doi:10.31838/jcdr.2021.12.01.20



Vancouver/ICMJE Style

Wulandari E, Hapsari RAF, Wulanuri I, Nasution AR. The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. . (2021), [cited May 01, 2021]; 12(1): 75-81. doi:10.31838/jcdr.2021.12.01.20



Harvard Style

Wulandari, E., Hapsari, . R. A. F., Wulanuri, . I. & Nasution, . A. R. (2021) The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. , 12 (1), 75-81. doi:10.31838/jcdr.2021.12.01.20



Turabian Style

Wulandari, Endah, Rr Ayu Fitri Hapsari, Ikrima Wulanuri, and Afdalia Rani Nasution. 2021. The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. Journal of Cardiovascular Disease Research, 12 (1), 75-81. doi:10.31838/jcdr.2021.12.01.20



Chicago Style

Wulandari, Endah, Rr Ayu Fitri Hapsari, Ikrima Wulanuri, and Afdalia Rani Nasution. "The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress." Journal of Cardiovascular Disease Research 12 (2021), 75-81. doi:10.31838/jcdr.2021.12.01.20



MLA (The Modern Language Association) Style

Wulandari, Endah, Rr Ayu Fitri Hapsari, Ikrima Wulanuri, and Afdalia Rani Nasution. "The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress." Journal of Cardiovascular Disease Research 12.1 (2021), 75-81. Print. doi:10.31838/jcdr.2021.12.01.20



APA (American Psychological Association) Style

Wulandari, E., Hapsari, . R. A. F., Wulanuri, . I. & Nasution, . A. R. (2021) The Role Cardioprotective of Edible Birdís Nest (Collocalia fuciphaga) Extract Through Suppression of Oxidative Stress. Journal of Cardiovascular Disease Research, 12 (1), 75-81. doi:10.31838/jcdr.2021.12.01.20