E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Research 


The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis

Svetlana S. Bunova, Ol'ga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko.

Abstract
The article shows the benefits of treatment with bisoprolol in achieving optimal heart rate at rest (55-60 per 1 minute) and identifies the prediction markers of its achievement in patients with stable coronary artery disease with post-infarction cardiosclerosis, taking into account clinical and genetic data: physical examination, 24-hour ECG monitoring, 5-minute study of heart rate variability, Arg389Gly polymorphism of the ADRB1 gene. The article proved that when a heart rate of 55-60 in 1 minute is reached, the antianginal effect of bisoprolol is expressed better, the markers of the prognosis in the achievement of this heart rate are determined.

Key words: heart rate, stable coronary artery disease, post-infarction cardiosclerosis, heart rate variability, Arg389Gly polymorphism of the ADRB1 gene.


 
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How to Cite this Article
Pubmed Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. J Cardiovasc. Dis. Res.. 2020; 11(4): 105-109. doi:10.31838/jcdr.2020.11.04.18


Web Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. http://www.jcdronline.org/?mno=6709 [Access: July 26, 2021]. doi:10.31838/jcdr.2020.11.04.18


AMA (American Medical Association) Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. J Cardiovasc. Dis. Res.. 2020; 11(4): 105-109. doi:10.31838/jcdr.2020.11.04.18



Vancouver/ICMJE Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. J Cardiovasc. Dis. Res.. (2020), [cited July 26, 2021]; 11(4): 105-109. doi:10.31838/jcdr.2020.11.04.18



Harvard Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko (2020) The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. J Cardiovasc. Dis. Res., 11 (4), 105-109. doi:10.31838/jcdr.2020.11.04.18



Turabian Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. 2020. The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. Journal of Cardiovascular Disease Research, 11 (4), 105-109. doi:10.31838/jcdr.2020.11.04.18



Chicago Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. "The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis." Journal of Cardiovascular Disease Research 11 (2020), 105-109. doi:10.31838/jcdr.2020.11.04.18



MLA (The Modern Language Association) Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko. "The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis." Journal of Cardiovascular Disease Research 11.4 (2020), 105-109. Print. doi:10.31838/jcdr.2020.11.04.18



APA (American Psychological Association) Style

Svetlana S. Bunova, Olga V. Zamahina, Nikolaj A. Nikolaev, Nina I.Zhernakova, Andrey A.Grishchenko (2020) The Prediction of the Bisoprolol Effectiveness in Patients with Stable Coronary Artery Disease with Post-Infarction Cardiosclerosis. Journal of Cardiovascular Disease Research, 11 (4), 105-109. doi:10.31838/jcdr.2020.11.04.18





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