E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny.

Abstract
Background;Early restoration of coronary flow in STEMI reduces mortality, high thrombus burden has a higher
incidence of no-reflow, stent thrombosis, LV dysfunction and mortality, thrombus aspiration can reduce thrombus
burden, but recent data suggest higher stroke incidence.
Objectives; We aimed in the study to determine the safety of the thrombus aspiration in high thrombus burden
lesions in primary PCI for STEMI patients.
Methods : One hundred patients were divided into two groups: Group 1: Aspiration catheter was used in 46 patients
with high thrombus burden, Group 2: 54 Patients with low thrombus burden, was managed with slandered PCI and
thrombus aspiration as bailout only. Group A: patients who developed cerebrovascular stroke, Group B: who didnít
develop stroke. Procedural complications and MACE data were obtained and follow up for stroke incidence for
30days.
Results: There were no differences between group-1 and group-2, or between group-A and group-B regards ST
segment resolution, intra-procedural complications, re-infarction. No differences between group-1 and group-2
regards death and stroke. Group-1 had lower age, higher DM and smoking prevalence, lower EF, and higher wall
motion score index (48.76vs53.68, P-value0.003)(29.6%vs54%, p-value0.012)(58%vs33%, pvalue0.011)(
47%vs51%, p-value0.018)(1.35vs1.21, p-value0.0029). Group-A had lower EF, TIMI III flow, higher
WMSI, higher no-reflow, and had higher mortality than group-B (34%vs50%, p-value0.0001)(40%vs81.3%, pvalue0.0165)(
1.65vs1.26, p-value0.00015)(60%vs3%, p-value0.00001)(40%vs2.1%, p-value0.011) respectively.
Conclusions: Thrombus aspiration didn't cause a significant increase in stroke rate at 30 days. LV systolic
dysfunction is an important risk factor for stroke during and after pPCI irrespective of the method of
revascularization. The stroke had higher mortality in pPCI patients.

Key words: We aimed in the study to determine the safety of the thrombus aspiration in high thrombus burden lesions in primary PCI for STEMI patients


 
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How to Cite this Article
Pubmed Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. J Cardiovasc. Dis. Res.. 2021; 12(4): 65-76. doi:10.31838/jcdr.2021.12.04.08


Web Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. http://www.jcdronline.org/?mno=89597 [Access: July 26, 2021]. doi:10.31838/jcdr.2021.12.04.08


AMA (American Medical Association) Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. J Cardiovasc. Dis. Res.. 2021; 12(4): 65-76. doi:10.31838/jcdr.2021.12.04.08



Vancouver/ICMJE Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. J Cardiovasc. Dis. Res.. (2021), [cited July 26, 2021]; 12(4): 65-76. doi:10.31838/jcdr.2021.12.04.08



Harvard Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny (2021) Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. J Cardiovasc. Dis. Res., 12 (4), 65-76. doi:10.31838/jcdr.2021.12.04.08



Turabian Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. 2021. Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. Journal of Cardiovascular Disease Research, 12 (4), 65-76. doi:10.31838/jcdr.2021.12.04.08



Chicago Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. "Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.." Journal of Cardiovascular Disease Research 12 (2021), 65-76. doi:10.31838/jcdr.2021.12.04.08



MLA (The Modern Language Association) Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny. "Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.." Journal of Cardiovascular Disease Research 12.4 (2021), 65-76. Print. doi:10.31838/jcdr.2021.12.04.08



APA (American Psychological Association) Style

Ahmed Gaafar, Khaled O. Abdulghani, Ahmed Basyouny (2021) Risk of Cerebrovascular Stroke with Primary Percutaneous Coronary Intervention Using Thrombus Aspiration Device in STEMI with High Thrombus Burden Lesions, A Single Center Experience.. Journal of Cardiovascular Disease Research, 12 (4), 65-76. doi:10.31838/jcdr.2021.12.04.08





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