Evaluation of thyroid function in patients with diabetes mellitus

Abstract

Background: Diabetes mellitus is a major health concern affecting a large proportion of the world's population. The present study was conducted thyroid function in patients with diabetes mellitus.
Materials & Methods: 78 type II diabetes mellitus patients of both genders were subjected to assessment of serum TSH (Thyroid Stimulating Hormone), free T3 (Triiodothyronine) and free T4 (Thyroxine) were assessed in the fasting serum samples using chemiluminescent immunoassay method technology.
Results: Out of 78 patients, 36 were males and 42 were females. The mean serum TSH was normal in 60, increased in 9 and decreased in 7. Free T3 was normal in 62, increased in 4 and decreased in 10 and free T4 was normal in 68, increased in 4 and decreased in 4 patients. The difference was significant (P< 0.05). Hypothyroidism was seen in 3,7,10 and 10 patients and
hyperthyroidism in 1,4,6 and 6 patients with duration of diabetes <1 year, 1-5 years and 5-10 years respectively.
Conclusion: The prevalence of thyroid dysfunction was higher in patients with diabetes. Therefore, thyroid hormone monitoring in type 2 diabetics is required to improve quality of life and reduce morbidity.