AN IMPACT OF CHROMIUM ON LIPID PROFILE AND GLYCEMIC LEVELS IN THE PATIENTS WITH TYPE 2 DIABETES MELLITUS

Abstract

INTRODUCTION: Chromium is a vital trace mineral that appears to play a significant role
in the modulation of insulin function and its impact on the metabolism of carbohydrates,
proteins, and lipids. It is a crucial element for enhancing the efficacy of insulin. Research
indicates that individuals with type 2 diabetes tend to have lower serum chromium levels
compared to those without the condition. Insulin resistance serves as a common factor among
various cardiovascular disease risk elements. Evidence suggests that chromium can diminish
insulin resistance and potentially lower the risk of developing cardiovascular disease and type
2 diabetes.
AIM AND OBJECTIVES: To study the impact of chromium supplementation of blood sugar
levels, insulin levels and lipid profile in type 2 diabetes mellitus patients.
METHODS: This study is a randomized controlled trial involving 60 participants diagnosed
with Type 2 Diabetes Mellitus, who were divided into two groups: one receiving chromium
supplementation and the other receiving a placebo. Fasting blood glucose levels, postprandial
blood glucose levels, and lipid profiles were assessed at both the commencement and
conclusion of the study. Participants were advised to maintain their usual dietary habits,
lifestyle, and medication regimen. No significant alterations were noted in weight, body mass
index, fasting blood glucose, or postprandial blood glucose levels in either group.
RESULTS: The findings of this study indicate that chromium supplementation did not produce
significant changes in blood glucose levels. Nevertheless, there were modest positive effects
observed regarding insulin resistance and lipid profiles associated with chromium
supplementation.
CONCLUSION: Supplementation with chromium may assist patients with Type 2 Diabetes
Mellitus in ameliorating the lipid profile disturbances and insulin resistance linked to the
disease.