Hyponatremia and its Prognostic Significance in Acute ST Elevation Myocardial Infarction

Abstract

Introduction: Cardiovascular disease is one of the leading causes of morbidity and mortality
across the world. Worldwide, there are 3 million sudden cardiac deaths per year due to acute
myocardial infarction.
Aim of the Study: To assess the Hyponatremia and its Prognostic Significance in Acute ST
Elevation Myocardial Infarction.
Material and methods: The present Prospective observational study was conducted among
patients with acute STEMI admitted to the emergency of Government medical college and
Hospital Jammu over a period of one year from November 2019 to October 2020 and total
number of 100 patients was taken. Complete Examination Done along with sodium
Concentration diagnosed.
Results: Maximum subjects were from the age group of 51-60 years (38%). 77% and 23%
were male and female respectively, hence showing male dominancy in our study. Mean
Killips score among the subjects with normal sodium, hyponatremia on admission and
hyponatremia within 72 hours was 1.03±0.22, 1.22±0.24 and 1.29±0.23 respectively. In our
study, mortality was reported among 7% of the subjects. Out of 7 subjects with mortality;
2.89%, 18.18% and 80% of the patients were having normal sodium, hyponatremia on
admission and hyponatremia within 72 hrs respectively with statistically significant
difference as p<0.05.
Conclusion: In our study we concluded that hyponatremia on admission or early
development of hyponatremia in patients with acute ST elevation myocardial infarction is an
independent predictor of 30-day mortality.