Phenotypic Determination of Methicillin-Resistant Staphylococcus Aureus Isolated From Tertiary Care Hospitals

Abstract

Context: Staphylococcus aureus (S. aureus) is an opportunistic pathogen. It can cause various infections in humans and animals. The threat of antibiotic resistance in S. aureus has risen over the years and the treatment costs have also spiralled up. Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to all β-lactam antimicrobials, and these strains contribute to both hospital-acquired and community-acquired infections.
Aim: This study aimed to determine the prevalence rate of methicillin-resistant Staphylococcus aureus in HA-MRSA and CA-MRSA.
Methods: MRSA were subjected to antibiotic susceptibility testing, and oxacillin discs and cefoxitin discs were used to detect them.
Results: Out of 150 Staphylococcus aureus isolates, 45 were MRSA. Of the 45 confirmed MRSA isolates, 18(40%) were HA-MRSA and 27 (60%) were CA-MRSA.
Conclusion: causes of nosocomial pathogens are responsible for causing various human infections that may range from minor skin diseases to life-threatening infections. In the
present era of antibiotic resistance, the emergence of multi-drug-resistant organisms is
becoming more common. Therefore, early detection is most important for treating, preventing and controlling such organisms