Comparative Efficacy of Mineral Trioxide Aggregate (MTA) and Biodentin in Apexification Procedures for Non-vital Immature First Permanent Molars: A Randomized Clinical Trial

Abstract

Objective: This randomized clinical trial aims to compare the efficacy of Mineral Trioxide Aggregate (MTA) and Biodentin in the apexification procedure for non-vital immature first permanent molars. Methods: A total of 141 participants meeting inclusion criteria were randomly assigned to either the MTA or Biodentin group. Standardized protocols were employed for apexification procedures, including thorough patient preparation, local anesthesia administration, access cavity preparation, cleaning, and disinfection of the root canal system, material placement, and radiographic confirmation. Primary outcomes included radiographic success and secondary outcomes encompassed clinical success, postoperative pain and time to complete apexification