A study of Maternal Lipid Profile and adverse pregnancy outcome

Abstract

Background : The maternal lipid profile has been increasingly recognized as a significant factor influencing pregnancy outcomes. Dyslipidemia during pregnancy can have adverse effects on both the mother and the fetus, potentially leading to complications such as preeclampsia, gestational diabetes, preterm delivery, and fetal growth restrictions. Understanding the relationship between maternal lipid levels and adverse pregnancy outcomes is crucial for developing strategies to improve maternal and fetal health. Aim and Objectives : To investigate the relationship between maternal lipid profiles and adverse pregnancy outcomes, emphasizing the potential mechanisms and clinical implications. Materials and Method : This study was a prospective cohort study conducted at the Obstetrics and Gynecology Department of Kakatiya Medical College/Hospital. Warangal, for the duration of one year. The study included 80 pregnant women attending the antenatal clinic at our institute, after getting informed consent from patients and approved by institutional Review board and meeting inclusion and exclusion criterial Results : majority of the patients were form age group of 26-30 Years, followed by 21 - 25 years, majority of the patients had normal BMI followed by Underweight(<18.5). Education showed graduation and above among most of the study participants followed by intermediate, and most of the patients underwent LSCS. study found that elevated levels of total cholesterol and LDL were significantly associated with an increased risk of preeclampsia and gestational diabetes. Higher triglyceride levels were also correlated with an increased likelihood of preterm birth and low birth weight. Conclusion : Assessing the serum lipid profile during pregnancy can serve as an early and cost-effective method to prevent the harmful effects of pregnancy-related hyperlipidemia.