“TO STUDY THE CORELATION BETWEEN SERUM MAGNESIUM LEVELS AND ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE”

Abstract

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a major global health
concern, characterized by persistent respiratory symptoms and airflow limitation. Acute
exacerbations of COPD can significantly impact disease progression and patient outcomes.
Magnesium, an essential mineral, has been implicated in various respiratory conditions, but its role in COPD exacerbations remains underexplored.
Aims and Objectives: This study aims to assess serum magnesium levels in patients with acute
exacerbations of COPD compared to those with stable COPD. Objectives include evaluating
correlations between magnesium levels and clinical parameters such as age, sex, smoking
habits, number of days of hospital stay, and arterial blood gas (ABG) analysis. Methodology: A cross-sectional study was conducted involving 90 COPD patients, with 45 experiencing acute exacerbations and 45 stable. Serum magnesium levels, demographics, smoking history, hospital stay duration and ABG parameters were recorded. Data were analyzed to compare magnesium levels and correlate findings with clinical parameters.
Results: Serum magnesium levels were significantly lower in the acute exacerbation group
compared to the stable group. Correlation analyses showed that lower magnesium levels were associated with longer hospital stays and worse ABG parameters.
Conclusion: This study suggests that lower serum magnesium levels are associated with acute
exacerbations of COPD. Monitoring magnesium levels could be beneficial in managing
exacerbations and improving patient outcomes.