EFFECT OF PLATELET-RICH PLASMA THERAPY IN KNEE OSTEOARTHRITIS

Abstract

Background: Aim: This study aimed to evaluate the effects of PRP on pain, joint function, and cartilage thickness in patients with knee OA over 12 months. Methods: In a randomized controlled trial conducted from 2020 to 2023 at IGIMS and PMCH in Patna, 100 patients with knee OA were assigned to either a PRP group (n=50) or a control group (n=50). PRP patients received three intra-articular injections, while controls received saline. Pain (VAS), function (WOMAC), and cartilage thickness (MRI) were measured at baseline, 3, 6, and 12 months.