ANTI-NUCLEAR ANTIBODIES IN DAILY CLINICAL PRACTICE: PREVALENCE IN A TERTIARY CARE HOSPITAL.

Abstract

Introduction: The presence of anti-nuclear autoantibodies (ANA) is closely associated with immune complex-mediated autoimmune conditions. Accurate detection and measurement of these autoantibodies play a pivotal role in both diagnosing and managing such diseases. The indirect immunofluorescence method has emerged as the gold standard for detecting ANA, facilitated by advancements in serological testing for autoimmune disorders. ANA screening, while non-specific, offers a reliable, rapid, and comprehensive assessment, revealing diverse patterns indicative of various autoimmune disorders.