COMPARATIVE STUDY OF INTRATHECAL DEXMEDETOMIDINE AND FENTANYL AS AN ADJUVANTS TO LEVOBUPIVACAINE HEAVY 0.5% FOR INFRA - UMBILICAL SURGERIES

Abstract

Background & Methods: The aim of the study is to compare Intrathecal Dexmedetomidine
and Fentanyl as an adjuvants to Levobupivacaine 0.5% for Infra - Umbilical Surgeries.
Clinical comparative study to evaluate the duration of analgesia, hemodynamic stability and
adverse effects of using intrathecal dexmedetomidine and fentanyl as an adjuvant to 0.5%
Levobupivacaine heavy for Infra umbilical surgery (general surgery and gynaecology
patient). The study participants were randomly divided into three groups.
Results: Onset of sensory block was earlier and duration of sensory block was maximum in
group C. Motor block regress faster in group A. postoperative analgesia was more in group C
and side effects was more in group B.
Conclusion: Incidence of Bradycardia and hypotesion was higher in the dexmedetomidine
group and itching and urinary retention was maximum in fentanyl group as compared to
dexmedetomidine group. Levobupivacaine with dexmedetomidine has prolonged duration of
sensory and motor blockade, good hemodynamic stability with decreased incidence of side
effect as compared to the fentanyl group. And levobupivacaine alone group.
So as compared to 25 mcg fentanyl. 5 μg of dexmedetomidine may be used as analternative
adjuvant to intrathecal 0.5% Levobupivacaine heavy in elective Infra umblical surgery hence,
dexmedetomidine seems to be an attractive alternative as Intrathecal adjuvant with
Levobupivacaine when compared with fentanyl