ASSOCIATION BETWEEN HYPOMAGNESEMIA AND COAGULOPATHY IN SEPSIS

Abstract

Background: Sepsis is defined as life-threatening organ dysfunction caused by a 
dysregulated host response to infection. Magnesium reportedly has immunomodulatory 
effects and is associated with dysregulated host response to infection and the pathophysiology 
of sepsis. Previous studies reported that hypomagnesemia was associated with lactic acidosis 
in sepsis, increased incidence of sepsis or septic shock in critically ill patients, and increased 
mortality in sepsis. Thus, this study is being conducted to explore the association between 
serum magnesium levels and coagulopathy in sepsis, outcomes.