Honeybee Venom: A Natural Remedy with Promising Therapeutic Potential

Abstract

Honeybee venom (apitoxin), composed of bioactive components such as melittin, apamin, and 
phospholipase A2, has been used in traditional medicine for centuries. Modern research 
explores its potential therapeutic applications for various diseases. Clinical studies and 
preclinical research have demonstrated its efficacy in treating conditions like rheumatoid 
arthritis, osteoarthritis, neurological disorders, and cancer. Despite its therapeutic potential, bee 
venom carries risks, including allergic reactions. Advances in synthetic venom production offer 
promising alternatives for broader and safer clinical applications. While more large-scale 
clinical trials are needed to confirm its efficacy and safety, honeybee venom remains a 
compelling candidate for novel treatments across a wide range of diseases.