A COMPARATIVE STUDY OF LATERAL INTERNAL SPHINCTEROTOMY WITH GLYCEROL TRINITRITE OINTMENT APPLICATION LOCALLY IN PATIENTS OF CHRONIC FISSURE IN ANO

Abstract

While 0.2% topical Glyceryl Trinitrate has been extensively studied for managing chronic 
anal fissures, less attention has been paid to its specific application methodology, dosage, and 
patient compliance, potentially contributing to higher recurrence rates and lower cure rates. This 
study addresses these gaps by comparing the healing outcomes of chronic anal fissures treated with 
0.2% Glyceryl Trinitrate (chemical sphincterotomy) versus surgical lateral internal sphincterotomy 
(surgical sphincterotomy) as its primary objective. Secondary objectives include assessing pain 
relief, reduction in rectal bleeding, risk of incontinence, and recurrence rates associated with both 
treatment methods.