Role of N-Acetyl Cysteine in Rodenticide poisoning

Abstract

Background: N-acetyl cysteine (NAC) has been shown to be effective in the treatment of non-acetaminopheninduced acute liver failure. NAC has anti-inflammatory, inotropic, and vasodilatory properties. It has also shown to
improve microcirculation and oxygen delivery in cases of liver failure. Rodenticide poisoning affects many vital
organs in the body including liver thereby causing acute liver failure with a high mortality rate. Our study aimed to
examine the clinical parameters of rodenticide poisoning patients and compare the severity of liver failure and the
outcome after NAC treatment