Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction: A case-control study.
DOI:
https://doi.org/10.48047/Keywords:
Myocardial infarction (MI); Low-density lipoproteins (LDL), Very low-density lipoproteins (VLDL), High-density lipoproteins (HDL), apolipoprotein-A; Malondialdehyde (MDA); Normolipidemic profile.Abstract
Aim: The present study outlines the many risk variables of myocardial infarction (MI) in the patient population. Blood lipid profiles were normolipidemic in the study’s subjects. Myocardialinfarction patients and controls werecompared concerning their lipid, lipoprotein, andapolipoprotein profiles. Materials & methods: In this study, 84 participants had their bloodcholesterol, Apolipoprotein-A, LDL, VLDL, HDL, triacylglycerols,andmalondialdehyde studied.
Out of the total number of participants, 42 were individuals who had suffered a myocardial
infarction (MI). In contrast, the other 42 were controls matched for age and sex. Results: Acute
myocardial infarction (MI) patients had significantly elevated levels of total cholesterol and
triacylglycerols (TAGs) (p <0.05) despite the presence of low-density lipoprotein (LDL) in their
blood. A significant difference was seen between the levels of apolipoprotein-A and low-density
lipoprotein in the MI group and those in the control group. Researchers found that those who had
a rapid heart attack exhibited significantly higher levels of malondialdehyde (p<0.05).Conclusion: For individuals diagnosed with risk factors, lipid profile monitoring, dietaryantioxidant consumption, and measurement of inflammatory markers can all help lower the risk ofmyocardial infarction (MI). Furthermore, early detection can prevent MI.
