2884 An Observational Study Determining the Correlation of Homocysteine and Lipid Profile Parameters with Ischemic Heart Disease

Abstract

Aim: The aim of the present study was to investigate the association of homocysteine level
and lipid profiles with ischemic heart disease.
Methods: This 12-month prospective case control study was undertaken at a tertiary care
hospital. The Department of Medicine accepted IHD patients. The research gathered data
from hospital inpatients and outpatients who met inclusion and exclusion criteria. Healthy
persons were picked among hospital workers and regular checkup patients.
Results: The homocysteine levels of the patients and controls differed significantly. As a
result, we discovered that in our investigation, increased homocysteine levels were
substantially linked to IHD. The chi-square test revealed no significant difference in
cholesterol levels between the patients and controls (p-value >0.05). As a result, there was no
evidence of a substantial link between hypercholesterolemia and IHD. Triglyceride levels did
not significantly vary between the patients and controls. HDL levels did not significantly vary
between the patients and controls.
Conclusion: According to this research, hyperhomocysteinemia is independently linked to
hypertriglyceridemia, high total cholesterol, high LDL, and low HDL values.