Frequency of Helicobacter pylori and cytotoxine associated gene A antibodies in patients with cardiac syndrome X

Abstract

Cardiac syndrome X (CSX) is a condition in which patients have the pain of angina despite normal coronary angiogram. Recently, Helicobacter pylori (H. pylori) bacteria has been associated with CSX. However, there is no obvious data about the frequency of its virulent strain (cytotoxine associated gene A: CagA) in patients with CSX. We surveyed the frequency of H. pylori and CagA antibodies in patients with cardiac syndrome X and healthy controls. Materials and Methods: Plasma samples from 100 CSX patients (61 females and 39 males; mean age: 51.8 12.3 years) and 100 healthy controls (61 females and 39 males; mean age: 48.9 6.3 years