Thalamic Network Pathology in Poststroke Epilepsy: Insights from Electroencephalographic Source Analysis.

Abstract

This study investigated alterations in the intrinsic thalamic network in poststroke epilepsy (PSE) using electroencephalography (EEG) source-level analysis. A retrospective observational study, following STROBE guidelines, enrolled 39 PSE patients and 34 stroke patients without epilepsy. Resting-state EEG data underwent source localization using minimum norm imaging and standardized low-resolution brain electromagnetic tomography (sLORETA). Thalamic network functional connectivity was assessed using coherence, with nodes defined by the Talairach atlas. Graph theory analysis compared network properties between groups.