METABOLITE IDENTIFICATION AND QUANTIFICATION OF VONOPRAZAN USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY

Authors

  • Alka Singh, Dr. Nalini Kanta Sahoo, Akhilesh Kumar Author

DOI:

https://doi.org/10.48047/

Keywords:

Vonoprazan, Metabolites, LC-MS/MS, Method Validation, Bioanalytical, Potassium-Competitive Acid Blocker

Abstract

Background: Vonoprazan fumarate (TAK-438F) is a novel potassium-competitive acid blocker (P-CAB) with superior efficacy in treating acid-related diseases. However, comprehensive metabolite identification and characterization remain limited in the literature,  particularly for Indian populations. 

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Published

2026-05-26