Significance of urine cytology in diagnosis of urothelial carcinoma of urinary bladder , Cytopathological correlation.

Abstract

Background: Urothelial carcinoma is the most widespread histological type of malignancy
affecting urinary bladder, the study aimed to examine different histopathological findings in
different bladder lesions and their correlation with exfoliative urine cytology. Material and
Methods: This study was run on 96 patients, clinically diagnosed or suspected to have urothelial
carcinoma of the urinary bladder be present at urologic sector in Gazy Al Hariri educational
hospital for surgical specializations in Baghdad Medical City. Urine cytology smears from all
these patients were studied. Cytological findings were correlated with histopathological findings.
Results: revealed that bladder tumors were commonly seen in males with average age of
presentation being the fifth decade, the most common type of carcinoma seen was low‑grade
urothelial carcinoma‑noninvasive type. Urine cytology was positive in 71.43% patients.
Conclusion: Urine cytology has a sensitivity and specificity of acceptable accuracy in the
diagnosis of cancer of the urinary bladder, and it provides a good implement to determine the
degree of tumor, especially high-grade. . But, it must be reported in a background of full clinical
information and must always be followed by histopathological examination.