Coronary Artery Disease Pattern using Gensini Score in Urban and Rural Indian Population

Abstract

Introduction:
Gensini scoring system is an objective method to determine the severity of Coronary Artery Disease (CAD)
based on angiographic findings. We are conducting this study as sparse data is available about association
between the severity of CAD in Urban & Rural population.
Objective:
To study the CAD pattern by angiogram using Gensini score in urban and rural Indian population.
Material and methods:
A cross-sectional study of all patients with CAD coming to Sri.Jayadeva Institute of Cardiovascular
Sciences and Research, Mysore from urban and rural areas presenting with known or suspected CAD with
chest pain suggestive of CAD and various investigations suggestive of CAD were screened. Patients with
evidence of CAD on coronary angiogram were included in the study.
Results:
Total 500 subjects who had evidence of CAD on Coronary angiogram were included in the study. Among
them, number of subjects from Urban is 250 and Rural is 250. Out of 250 subjects in urban 73.6% (184)
were male and 26.4% (66) were female subjects. Of the 250 subjects in rural 76% (190) were male and
24% (60) were female. Mean Gensini score in urban population is 40.69 and rural population is 22.85
which was significantly more in urban than rural population (p<0.0001). Number of diseased vessels in
Urban is 1.808 and rural is 1.456 which was significantly more in urban than rural population
(p<0.0001).Gensini Score was compared with each risk factors between urban and rural subjects and it is
significantly more in urban population in 40-70 years age group, among males, across all risk factors, BMI
>25, sedentary life style, DM, HTN, Dyslipidemia, F/H/O CAD, Smoking compared to rural population.
The Genisini score is high in urban than rural subjects and indicating severity of coronary artery disease is
more in urban population compared to rural population.
Conclusions:
Gensini score is more in urban population compared to rural population indicating more coronary lesions in
urban population. Gensini Score was compared with each risk factors between urban and rural subjects and
it is significantly more in Urban than Rural population.