AUTOPHAGY, CANCER AND ASSOCIATED CHEMOTHERAPY

Abstract

Autophagy is involved in many biological processes, and its dysregulation has been linked to carcinogenesis, 
tumor-stroma interactions, and cancer therapy resistance.. Autophagy also appears to be a major regulator of the 
tumor microenvironment and cellular drug response in a number of cancer types, according to an increasing 
body of research. Our comprehension of the autophagic mechanism, on the other hand, remains limited. The 
purpose of this investigation was to establish a link between autophagy and cancer, as well as to investigate the 
mechanism of action of anticancer drugs in relation to autophagy.