Efficacy Of Radiofrequency Catheter Ablation Versus Antiarrhythmic Drugs In Treating High Burden Premature Ventricular Contractions In Children With Structurally Normal Heart
DOI:
https://doi.org/10.48047/Keywords:
Premature ventricular contractions; radiofrequency catheter ablation; antiarrhythmic drugs; children; radiofrequency catheter ablation.Abstract
Background: Scarce literature on whether antiarrhythmic drugs (AADs) or radiofrequency catheter ablation
(RFCA) is more efficacious when treating children suffering from a high load idiopathic premature ventricular
contractions (PVCs) with many questions remain unanswered in this age group.
Objectives: The purpose of this study was to compare the efficacy of RFCA and AADs on high burden
idiopathic PVCs in children.
Methods: A total of 60 eligible child ≤18 years with High burden PVCs (≥10% of total beats per day) that
were treated by either AADs (group A) or RFCA (group B). Both the baseline and follow-up measurements
were taken. After gathering clinical complaints, a physical examination, a repeat standard ECG, a standard
or 12-lead Holter recording, and echocardiography were all conducted.
Results: Among RFCA (n=30) and AADs (n=30) groups, treatment success was 80.0% and 20.0%
respectively, while AADs medications cessation was 73.3% and 26.7% respectively, the differences were
statistically significant.
Conclusion: In terms of PVC reduction and, as a result, AADs medication cessation post-ablation, RFCA
appears to be more effective than AADs. It was a safe and extremely successful therapeutic option
performing RFCA in children to use traditional mapping.




