Histological changes in the internal organs of rats during the experimental study of the acute toxicity of the new G10 substance
DOI:
https://doi.org/10.48047/Keywords:
acute toxicity, hazard class, substance G10, preclinical study,submucosal layer, Calligonum plant,intraperitoneally, enteral substanceAbstract
The article presents the results of experimental studies devoted to the study of morphological changes in the internal
organs of rats after the introduction of Substance G 10. The purpose is to determine the toxicity of the new substance
G10 extracted from the leaves of the Calligonum plant on the basis of morphological studies of the internal organs of
laboratory rats under acute experimental exposure to the substance under study. The materials and methods used are,
the object of the study is the substance G10 from the Calligonum plant, which is a brown powder, odorless, poorly
soluble in water. The substance was provided by the research Institute of Bioorganic chemistry of the L. N.
Gumilyov ENU. The work was carried out in accordance with the ethical and scientific requirements of preclinical
studies on animals.
