T Cells In Chronic HCV Genotype 4 Infected Patients

Abstract

The T cell responses unique to the Hepatitis C virus (HCV) are strongly related to the
disease's medical history. While T cell responses are often wide and multi-specific with self-limiting
infections, in the chronic stage they show many unique functional impairment characteristics.
Furthermore, by acquiring mutations in exhaust inside T targeted epitopes, HCV adapts quickly to an
immunological pressure. Much of our existing information about HCV specific T cell responses is
assumed to pave the path for a therapeutical vaccine at long last.