Predictors Of Successful Radiofrequency Catheter Ablation Of Premature Ventricular Complexes

Abstract

Introduction Cases with an elevated burden of premature ventricular complexes PVC can benefit from catheter ablation, which was proven to be an efficient as well as therapeutic strategy to improve symptoms while simultaneously reducing PVC burden. Aim: The objective of this research is to determine the predictors of successful radiofrequency catheter ablation of premature ventricular complexes. Participants &Methods: A group of 100 subjects with a burden PVCs greater than 15%, who were scheduled for a conventional or 3D ablation at electrophysiology unit of Ain Shams University between 2018 and 2020, have been recruited in the current study. Success has been identified as acute elimination of PVCs in Cath-lab with a 30 minutes waiting period and PVCs burden <3% on follow up Holter recording. Results: The success rate was 83% among 100 patients (mean age 41.31 ± 17.69 years, 52% female patients), with 68% of the patients undergoing conventional ablations. Success was predicted by age (<58 years), outflow tract (OT) origin of PVCs, and the existence of a pre-QRS signal on the ablation catheter> 33msec (P- value < 0.001). No statistical difference between conventional ablation as well as 3D ablation was detected in this study regarding predictors of success. Conclusion: Age, Origin of PVCs and pre-QRS signal are predictors of success of PVCs ablation.