PREVALENCE OF DCM IN PUNE POPULATION AND FACTORS AFFECTING ITS PHENOTYPIC EXPRESSIONS

Abstract

Dilated Cardiomyopathy (DCM) is an irreversible and slowly progressive disease that occurs at any
stage of life. DCM is characterised by left ventricle enlargement and systolic dysfunction. There is no
study of DCM that has been carried out in the Pune population. Therefore, the present study was
undertaken to examine the clinical and demographic profile of patients with dilated cardiomyopathy in
the fast-urbanizing Pune population.
Methods:
The Institutional Human Ethics committee of Bharti Hospital, Pune approved the present study. A
study was carried out for a period of five years (2016-2020). Data was collected from the Medical
records Department (MRD) of Bharti hospital, Pune. Data were analysed using software past 3 and
SPPS.
Results:
Among all cardiovascular diseases, DCM was the second commonest disease in the Pune population. A
total of 165 phenotypically positive DCM patients were considered for the current study. A higher
percent of hypertension, diabetes mellitus, and lower ejection fraction were observed above the age
group of 40 years. We observed that DCM patients had a progressive decrease in EF and a progressive
increase in the size of LVIDd and LVIDs with age.
Conclusion:
HTN, DM, and age-related co-morbidities are the major risk factors for DCM in the Pune population
with major phenotypic expressions such as left ventricle dilation, reduced ejection fraction, and risk of
heart failure.