CARDIOVASCULAR DISEASE RISK FACTORS AND TRACE ELEMENTS: A SYSTEMATIC REVIEW WITH SPECIAL EMPHASIS ON SOUTH ASIAN POPULATION

Abstract

Background: The neoteric industrialization has deliberately uplifted the exposure of several heavy trace elements
leading to multiple ecological and public health burdens like cardiovascular diseases (CVDs). Aim of the study:
Thus, the present review aims to elucidate the extent of association of trace elements with CVD risk factors.
Methodology: 78 full-length papers considering only human subject from peer-reviewed journals were reviewed
using Google Scholar, PUBMED, Research Gate and by manual searching. Result: Findings suggest elevated level
of the essential trace elements like zinc, copper, chromium, selenium, iron and manganese as well as the noxious
metals like mercury, cadmium and lead alter glucose and insulin homeostasis, lipid metabolism, hypertensive
disorders and obesity.
Conclusion: Hence, it seems reasonable to argue that trace elements have significant contribution in developing
CVD.