BISPHOSPHONATES AND PERIODONTICS

Abstract

Bisphosphonates which inhibit bone resorption are the group of drugs widely used in the management
of systemic metabolic bone disease such as bone metastases, osteoporosis, Paget’s disease etc. Their
ability to induce osteoblastic differentiation and inhibit recruitment of osteoclasts, bisphosphonates
have provided a management strategy where it can be used alone or in conjunction with regenerative
materials around bone defects both in periodontitis as well as around implants. The objective of this
review article is to discuss about various groups of bisphosphonates, their actions and their potential
use in the field of periodontics.