COMPARISONOFLEFTVENTRICULARHYPERTROPHYAM ONGNORMOTENSIVETYPE 2 DIABETES MELLITUSPATIENTS WITHTHAT OF AGE-ANDGENDERMATCHEDNON-DIABETICPATIENTS.

Authors

  • Ashfaq Ahmad, Fazal Shafiq,Syed Arshad Ullah,Afiat Shaheen ,Syed Noor Ullah Shah Fazal Saboor ,Noor Alam ,Muhammad Ismail ,Seraj Uddi ,Nget Sreynith ,Sher Azim. Author

DOI:

https://doi.org/10.48047/

Keywords:

Left ventricular hypertrophy, Diabetes mellitus, left ventricular mass, left ventricular mass index,

Abstract

Background: Adverse cardiac outcomes like morbidity and mortality are eventually associated with Type 1 or
Type 2 DM. The cardiovascular risk may eventually be increased with increased LVM. LVM is a lifethreatening prognostic sign because of developing ventricular arrhythmia, myocardial ischemia, CHD, and HF.
Aim: This cross-sectional study aimed to evaluate the prevalence and risk factors for the development of LVH
in age-and gender-matched normotensive population with T2DM and comparison of LVH among diabetic and
non-diabetic normotensive patients
Methods: A total of 300 populations were included in this study.150 who were non-hypertensive with known
T2DM and a similar number of healthy age- and gender-matched, non-diabetic, and normotensive controls. All
the subjects of known diagnosed with T2DM with on oral or injectable anti-diabetic medication or patients with
fulfilling the American Diabetic Association criteria for DM without any medical therapy. The baseline data
were collected and LVM and LVMi were calculated by using echocardiographic parameters and BSA.
Results: LVM and LVMI were significantly higher in T2DM patients compared with the age-and gendermatched control population (231.7±30.38 vs 190.8±25.18 g/m2 with all P<0.0001) and (134.1±25.43 vs
70.61±14.57 with P<0.0001) respectively.Conclusion: LVM and LVMIwas significantly higher in T2DM patients without HTN, IHD, and other diseases.The prevalence of LVH is almost the same in both genders. Prevalence of left ventricular mass in T2DM
patients were high without other major complications. It’s important to rule out the prognosis of LVM in the
diabetic population to overcome cardiovascular adverse events and morbidity and mortality.

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Published

2021-03-13